Modified on: February 27th, 2023
This report provides exploratory and preliminary correlation analyses between sex hormones and T2 final hippocampal subfield volume data from the Healthy Aging Study sample that have completed the spatial navigation study.
Cleaning data steps included (T2 subfields):
Filter participants that have useable T2 subfield data from scan and completed spatial navigation behavior
Select sex hormone measures from when spatial study was conducted
Values were already averaged together (left and right) and already corrected with TIV
For left and right subfields, they have already been corrected with TIV
Calculating Total Hippocampal Volume:
Sum up the averaged CA1, CA23, DG, SUB to get T2 total hippocampal volumes
Left and right volumes are by adding respective left and right subfields
Calculating Total MTL:
Sum up the averaged CA1, CA23, DG, SUB, ERC, PHC, PRC to get MTL volume
Left and right volumes are by adding respective left and right subfields
| Sex | n | Mean Age | SD Age |
|---|---|---|---|
| Female | 33 | 50.15 | 3.09 |
| Male | 19 | 49.74 | 3.33 |
Above table shows the table of sample size and mean and standard deviation of age by sex for overall group who have completed spatial behavior and have a useable T2hipp scan.
Shapiro-Wilk’s test reveal that DSP solution index for overall and women and DSP path efficiency for women were also not normally distributed. Behavior and volume correlations will be Spearman rank
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Spearman except for men (Pearson).
All correlations were Spearman except for men (Pearson).
All correlations were Spearman except for men (Pearson).
All correlations are Pearson except for women (Spearman)
All correlations are Pearson except for women (Spearman)
All correlations are Pearson except for women (Spearman)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations are Pearson except for women/repo (Spearman)
All correlations are Pearson except for women/repo (Spearman)
All correlations are Pearson except for women/repo (Spearman)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations Pearson except for women/repo (Pearson)
All correlations Pearson except for women/repo (Pearson)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations Pearson except for women/repo (Spearman)
All correlations Pearson except for women/repo (Spearman)
All correlations Pearson except for women/repo (Spearman)
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations are Pearson except for women/repo
All correlations are Pearson except for women/repo
All correlations are Pearson except for women/repo
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations are Pearson except for women/repo
All correlations are Pearson except for women/repo
All correlations are Pearson except for women/repo
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
Overall and men are Pearson, women and repo groups are Spearman
Overall and men are Pearson, women and repo are Spearman
Overall and men are Pearson, women and repo are Spearman
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Pearson except for women/repo
All correlations were Pearson except for women/repo
All correlations were Pearson except for women/repo
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Pearson except for women/repo
All correlations were Pearson except for women/repo
All correlations were Pearson except for women/repo
Sample included HAS participants who had a T2 hipp scan and completed spatial navigation behavior.
DSP wayfinding success was significantly negatively correlated with average ERC volume for overall. It was also negatively correlated with average PHC volume for women.
DSP solution index was significantly negatively correlated with DG volume for overall and posts (right volume) and for men (average volume). It was positively correlated with right PRC volume for pres.
DSP path efficiency was positively correlated with average and left ERC volume for overall, women and for pres (average volume only). It was also negatively correlated with average and left PHC volume for women.